Krishnan Sampath, Ph.D

Chief Technology Officer (BioTherapeutics Innovation) at Dechra

Washington DC-Baltimore Area, United States

About Krishnan Sampath, Ph.D

Krishnan Sampath, Ph.D is Chief Technology Officer (BioTherapeutics Innovation) at Dechra. Location: Washington DC-Baltimore Area, United States.

*Innovation-driven biotechnology executive and CTO with 25+ years of leadership across biologics development including formulation and analytical methods, manufacturing, supply chain, quality, and regulatory functions for human and animal health therapeutics. *CTO, Biotherapeutics Innovation at Dechra, leading end-to-end CMC development and manufacturing strategy and execution for an innovative monoclonal antibody pipeline spanning early research through late-stage development under FDA, EMA, and USDA regulatory frameworks. *Proven architect of successful product commercialization, contributing to 7 BLA approvals, 40+ IND/IMPD submissions, and numerous FDA interactions, including pre-BLA meetings and Pre-Approval Inspections (PAIs). *Strategic leader in biologics development and manufacturing, building global CRO/CDMO networks and commercialization strategies across diverse modalities, including mAbs, ADCs, bispecifics, fusion proteins, cell therapies, peptides, emerging modalities, and small molecules. *Experienced enterprise leader with a track record of building and leading high-performing global matrix organizations while managing more than $100M in development, operations, and capital investment budgets. *Subject matter expert in Quality by Design (QbD) and CMC excellence, developing robust formulation, process, validation, and control strategies that accelerate development while ensuring regulatory compliance and product quality. *Trusted scientific advisor and industry thought leader, supporting oncology and immunology programs, serving on the Editorial Advisory Board of the Journal of Pharmaceutical Sciences, and providing strategic guidance on technical development and operations. *Experienced in business development and corporate strategy, supporting M&A, partnering, licensing, and due diligence activities to evaluate and advance innovative therapeutic assets. *Recognized innovator and mentor with 25+ peer-reviewed publications, patents, and a demonstrated commitment to fostering scientific excellence, academic collaboration, talent development, and adoption of transformative technologies.

Skills

  • Biopharmaceuticals
  • Biotechnology
  • Protein Chemistry

Additional experience

  • Principal Consultant and Owner

    SSK BioSolutions, LLC

    Started January 2022

Education

  • Ph.D Pharmaceutical Sciences , University of Colorado Health Sciences Center
  • Executive Education Certificate, The Wharton School