Chandra Vargeese
Chief Technology Officer and Head of Platform Discovery Sciences at Wave Life Sciences
Cambridge, Massachusetts, United States
About Chandra Vargeese
Chandra Vargeese is Chief Technology Officer and Head of Platform Discovery Sciences at Wave Life Sciences. Location: Cambridge, Massachusetts, United States.
Senior Research and development leader with 25 years of experience in research and development of nucleosides and nucleic acid based therapeutics including aptamers, siRNAs, ribozymes, antisense and mRNA. Recognized thought leader in application of various nucleic acid platform technologies from basic research and discovery to commercial products with strong track record of patents and publications. Areas of expertise include: • Directed and performed research in various nucleic acid based therapeutics • Co-invented Macugen, FDA approved aptamer drug for Age Related Macular Degeneration (AMD) • Oligonucleotide design, nucleic acid modification, synthesis and large scale production of drugs to support clinical trials • Invented and developed nucleic acid delivery technologies including targeted delivery, liposomes, polymer and conjugates • Pharmaceutical process research and development and manufacturing • Extensive experience in nanoparticles for delivering nucleic acids • Strong analytical skills to characterize nucleic acids and various nanoparticles • Communicating effectively and working collaboratively across broad range of functions and external collaborations • Recruiting and leading high-performance research and development organizations
Skills
Additional experience
Senior Vice President and Head of Research
Wave Life Sciences
Started August 2014
Education
- Post Doctoral Fellow, University of Rhode Island
- Doctor of Philosophy (PhD), Indian Institute of Science (IISc)